The OrthoXenoBank® is a collection of orthoxenografts® that Xenopat offers its customers. A summary of the available orthoxenografts® can be found in the Table below, however if more details are needed please do not hesitate to contact us.
The OrthoXenoBank® is composed of more than 350 models, which represent the most frequent histological subtypes of tumors found in the following locations: the colon, lungs, ovaries, pancreas, endometrium, head and neck, liver, and in germ cells, among others. All the tumor types collected in OrthoXenoBank® are classified according to histological subtypes and are characterized at genetic level for the most relevant mutations reported in each tumor subtype.
** Endogenous refractary tumors.
OrthoXenoBank® tumors are also classified according to their degree of sensitivity/resistance to different standard chemotherapy treatments. The OrthoXenoBank® contains some tumors developed by patient’s resistance to standard lines of chemotherapy.
Moreover, the OrthoXenoBank® contains chemotherapy sensitive and resistant orthoxenograft® pairs, obtained in vivo through repetitive exposure of the sensitive orthoxenograft® to treatment.